Isolation of a tetrasaccharide common to MM, NN and MN antigens
| Autor: | A.M. Adamany, R.H. Kathan |
|---|---|
| Rok vydání: | 1969 |
| Předmět: |
Electrophoresis
Chemical Phenomena Stereochemistry Biophysics Disaccharide Neuraminidase Oligosaccharides Sialidase Biochemistry chemistry.chemical_compound Sodium borohydride Mole Methods Humans Antigens Molecular Biology Glycoproteins Bacteria Periodic Acid Periodate Galactose Hexosamines Cell Biology Blood Proteins MNS antigen system Chromatography Ion Exchange Amino Alcohols Sialic acid carbohydrates (lipids) Models Structural Chemistry chemistry Viruses Blood Group Antigens Chromatography Gel Neuraminic Acids |
| Zdroj: | Biochemical and biophysical research communications. 37(1) |
| ISSN: | 0006-291X |
| Popis: | A tetrasaccharide consisting of 2 moles sialic acid, 1 mole galactose, and 1 mole N-acetylgalactosaminol was isolated from MM, NN, and MN blood group substances subsequent to degradation with alkaline sodium borohydride. Upon removal of sialic acid with bacterial or viral sialidases, a disaccharide, galactosyl-N-acetylgalactosaminol, was obtained. Periodate oxidation studies suggested that the two sialic acid residues are linked to galactose and N-acetylgalactosaminol, respectively. A tentative structure is proposed. |
| Databáze: | OpenAIRE |
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