Comparison of elastography based on transvaginal ultrasound and MRI in assessing parametrial invasion of cervical cancer
| Autor: | Wei Ding, Xi Ma, Yu-chun Zhu, Jun Shao, Qi Li, Hong-yan Wang, Jian-liang Wang, Jun-kang Shen, Hou-sheng Zhang |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
medicine.medical_specialty Physiology Uterine Cervical Neoplasms 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine McNemar's test Figo staging Physiology (medical) medicine Humans Aged Neoplasm Staging Ultrasonography Cervical cancer medicine.diagnostic_test Parametrial business.industry Magnetic resonance imaging Hematology Middle Aged medicine.disease Magnetic Resonance Imaging Predictive value Transvaginal ultrasound 030220 oncology & carcinogenesis Vagina Elasticity Imaging Techniques Female Radiology Elastography Cardiology and Cardiovascular Medicine business |
| Zdroj: | Clinical Hemorheology and Microcirculation. 66:27-35 |
| ISSN: | 1875-8622 1386-0291 |
| Popis: | The purpose of this study was to evaluate the clinical value of transvaginal elastography (TVES) combined with high-resolution transvaginal ultrasound (TVS) in the detection of parametrial invasion in cervical cancer and to compare the diagnostic performance with magnetic resonance imaging (MRI).52 women with histologically confirmed cervical cancer over a 2-year period were staged using International Federation of Gynecology and Obstetrics (FIGO) criteria and underwent MRI and TVES combined with TVS according to a standardized protocol before treatment. When assessing parametrial involvement with TVS, MRI, and combination of TVES and TVS, the findings were recorded and compared with histopathological results after surgery in early-stage disease (stage⩽IIa). Sensitivity, specificity accuracy, positive predictive value (PPV) and negative predictive value (NPV) were calculated for each method independently; subsequently, a matched-sample analysis was performed by using McNemar's test or chi-square test.Of 52 patients, 39 were early-stage disease (stage⩽IIa), and 13 were advanced-stage disease (stage⩾IIb) according to conventional FIGO staging. For the detection of parametrial infiltration, both the diagnostic sensitivity of MRI and the combination of TVS and TVES were statistically higher than alone TVS in early-stage of cervical cancer (P = 0.03 0.05). Both MRI and the combination of TVS and TVES had a sensitivity of 72.73%; specificity rates of 82.14% for MRI and 78.57% for the combination of TVES and TVS; and the diagnostic accuracy rates of 79.49% for MRI and 76.92% for the combination of TVES and TVS. A matched sample analysis revealed no statistically significant difference between the diagnostic performance of MRI and the combination of TVES and TVS in the assessment of parametrial invasion (all P values 0.05).TVES combined with TVS performed by a dedicated gynecologic radiologist should be considered a promising and economic method for pre-operative work-up for cervical cancer. |
| Databáze: | OpenAIRE |
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