Albumin levels and its association with outcomes in a Serie of Covid-19 patients in Spain
Autor: | L. García Aragonés, L. M. Garcia Blasco, J. G. Arias Martínez, R.P. Quílez Toboso, Y. Rodríguez Marín, P. Sánchez Sáez, J. J. Alfaro Martínez, P. Pérez Díez |
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Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
Nutrition and Dietetics biology Coronavirus disease 2019 (COVID-19) business.industry Proportional hazards model Endocrinology Diabetes and Metabolism C-reactive protein Hazard ratio Albumin Retrospective cohort study Intensive care unit Article law.invention law Internal medicine Cohort biology.protein Medicine business |
Zdroj: | Clinical Nutrition ESPEN Clinical Nutrition Espen |
ISSN: | 2405-4577 |
DOI: | 10.1016/j.clnesp.2020.09.646 |
Popis: | Rationale: Several factors related to the prognosis of COVID-19 have been described Albumin is a nutritional parameter but it’s also known its usefulness as a prognostic factor in several diseases Methods: This is a retrospective observational study of a cohort of 533 hospitalized patients in a tertiary hospital between 1 March 2020 and 15 April 2020 with diagnosis of COVID-19 Laboratory data were collected such as albumin (Normal Values [NV] 3 5-5 2 g/dL) and C reactive protein (CRP, NV 0-5 mg/dL) within 48 hours of admission Clinical outcomes were defined as mortality or admission to an intensive care unit (ICU) Statistics were done using t test, Cox regression and Pearson correlation The aim of the study was to evaluate the relationship between albumin and CRP and the prognosis of COVID-19 In addition, it was studied the relationship between albumin, CRP and other parameters such as hospital stay and age Results: Among the patients who died the mean albumin level was lower in comparison with the survivors group (3 28 +- 0 37 g/dL versus 3 54 +- 0 43 g/dL, p |
Databáze: | OpenAIRE |
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