Comparison of infection eradication rate of using articulating spacers containing bio-inert materials versus all-cement articulating spacers in revision of infected TKA: a systematic review and meta-analysis
Autor: | Yi He, Qiang Yu, Ma-Yao Luo, Anli Lai, Qinyuan Hu, Shaoyu Wu, Jing Tian, Yang Sun |
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Rok vydání: | 2019 |
Předmět: |
Male
Reoperation medicine.medical_specialty Prosthesis-Related Infections Knee Joint Total knee arthroplasty Dentistry Biocompatible Materials Cochrane Library Prosthesis Design 03 medical and health sciences 0302 clinical medicine Recurrence medicine Humans Infection control Orthopedics and Sports Medicine Arthroplasty Replacement Knee Aged 030222 orthopedics business.industry Quality assessment Bone Cements Retrospective cohort study 030229 sport sciences General Medicine Treatment period Anti-Bacterial Agents Treatment Outcome Meta-analysis Orthopedic surgery Female Surgery Knee Prosthesis business |
Zdroj: | Archives of Orthopaedic and Trauma Surgery. 139:695-707 |
ISSN: | 1434-3916 0936-8051 |
DOI: | 10.1007/s00402-019-03121-x |
Popis: | To assess the infection eradication rate when using two types of articulating spacers (prosthetic articulating spacers and all-cement articulating spacers) in two-stage revision of infected total knee arthroplasty (TKA). We comprehensively searched PubMed, Embase, and the Cochrane Library databases and performed a systematic review and meta-analysis of retrospective comparative studies assessing two types of articulating spacers. A quality assessment of the included studies was performed following the STROBE statement. Thirty retrospective studies, including a total of 821 knees, were identified. The pooled infection control rates in stage I were as follows: 0.98 (95% confidence interval [CI], 0.97 to 1.00) and 0.98 (95% CI, 0.96 to 0.99) for the prosthetic articulating spacer group and all-cement articulating spacer group, respectively. The pooled postoperative reinfection rate was 0.05 (95% CI, 0.03 to 0.08) for the prosthetic spacer group and 0.03 (95% CI, 0.01 to 0.06) for the all-cement spacer group. Results of the subgroup analyses showed that the weight of the antibiotic cement, antibiotic type, mean period of spacers in situ, postoperative antibiotic treatment period, and postoperative antibiotic treatment approach had no effect on the reinfection rates (p |
Databáze: | OpenAIRE |
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