Evaluation of the effect of the severity of diabetic retinopathy on microvascular abnormalities and vascular density using optical coherence tomography angiography
| Autor: | Raja Zhioua, Héla Kaoual, Imène Zhioua Braham, M. Boukari |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Capillary plexus Endocrinology Diabetes and Metabolism chemistry.chemical_compound Endocrinology Disease severity Ophthalmology Diabetes mellitus Retinal capillary Internal Medicine medicine Intraretinal microvascular abnormalities Diabetes Mellitus Humans Fluorescein Angiography Diabetic Retinopathy business.industry Retinal Vessels Retinal General Medicine Diabetic retinopathy Optical coherence tomography angiography medicine.disease chemistry business Microvascular Density Tomography Optical Coherence |
| Zdroj: | Acta diabetologica. 58(12) |
| ISSN: | 1432-5233 |
| Popis: | To quantify and to study the relationship between retinal microvascular changes and different stages of diabetic retinopathy (DR) using optical coherence tomography angiography (OCTA). This prospective observational study included the eyes of patients with different stages of DR. OCTA was performed in all eyes using a 9 × 9 mm protocol. We analyzed the superficial and deep retinal capillary plexuses, for the following OCTA parameters: number of microaneurysms (MA), number of intraretinal microvascular abnormalities (IRMA), the total surface of capillary non-perfusion (CNP) areas, and vascular density (VD). The association between those parameters and the severity of DR was studied. A total of 70 eyes of 45 patients were included. The number of MA in the superficial capillary plexus (SCP) showed a significant association with DR severity (p = 0.03). The number of IRMA and the total surface of CNP areas were associated with the severity of DR in both plexuses (p = 0.019 in the SCP and p = 0.044 in the DCP for IRMA; p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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