Non-mosaic Klinefelter syndrome and successful testicular sperm extraction-intracytoplasmic sperm injection procedure: case report

Autor: Sherif Khattab, Ahmed M. Abdelhak, Ismail I Aboulfotouh, Mohamed A. F. Youssef, Amir A. F. Mady
Rok vydání: 2011
Předmět:
Zdroj: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 27(11)
ISSN: 1473-0766
Popis: Introduction. Klinefelter syndrome is the commonest chromosomal cause of non-obstructive azoospermia. Despite reports that these men can have children using assisted reproduction techniques, it is not common practice in the Egypt to offer sperm retrieval to these men.Design. Case report.Setting. Private IVF center (EIFC-IVF) and a university hospital.Patient. A 24-year-old woman and a 29-year-old man with non-mosaic Klinefelter syndrome.Intervention. Testicular sperm extraction followed by intracytoplasmic sperm injection and embryo transfer (TESE-ICSI).Results. Fifteen immotile sperms were found, five oocytes were injected, and three embryos were transferred. Now the pregnancy is progressing beyond 20 weeks.Conclusion. Spermatozoa from a patient with non-mosaic Klinefelter syndrome retrieved through TESE can lead to pregnancy.
Databáze: OpenAIRE
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