Directed evolution to improve protein folding in vivo
Autor: | James C.A. Bardwell, Veronika Sachsenhauser |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Protein Folding Computer science Green Fluorescent Proteins Context (language use) Computational biology Biosensing Techniques Protein Engineering Article 03 medical and health sciences Protein stability Structural Biology In vivo Genes Reporter Chaperonin 10 Escherichia coli Molecular Biology Staining and Labeling Extramural Protein Stability Chaperonin 60 Directed evolution Folding (chemistry) Kinetics 030104 developmental biology Thermodynamics Protein folding Directed Molecular Evolution Biotechnology |
Zdroj: | Current opinion in structural biology |
ISSN: | 1879-033X 0959-440X |
Popis: | Recently, several innovative approaches have been developed that allow one to directly screen or select for improved protein folding in the cellular context. These methods have the potential of not just leading to a better understanding of the in vivo folding process, they may also allow for improved production of proteins of biotechnological interest. |
Databáze: | OpenAIRE |
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