Successful cure of dermatomyositis after treatment of nonseminomatous testicular cancer
| Autor: | Atsushi Yoshinaga, Nobuyuki Ishii, Takumi Yamada, Toru Watanabe, Rena Ohno, Tetsuo Hayashi |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Male endocrine system medicine.medical_specialty Pathology Urology medicine.medical_treatment Physical examination Gastroenterology Dermatomyositis Testicular Neoplasms Carcinoma Embryonal Internal medicine Antineoplastic Combined Chemotherapy Protocols Carcinoma Humans Medicine Ifosfamide Testicular cancer Etoposide Chemotherapy medicine.diagnostic_test business.industry Cancer medicine.disease Treatment Outcome Cisplatin business Orchiectomy medicine.drug |
| Zdroj: | International Journal of Urology. 12:593-595 |
| ISSN: | 1442-2042 0919-8172 |
| DOI: | 10.1111/j.1442-2042.2005.01105.x |
| Popis: | Although the association between dermatomyositis and cancer is well recognized, there have been a limited number of reports of dermatomyositis associated with testicular cancer. We report the case of a 31-year-old man who was diagnosed with dermatomyositis. Because the patient's serum levels of alpha-fetoprotein and human chorionic gonadotropin beta subunit were elevated, the patient was referred to our department. Physical examination revealed an induration (2 cm x 2 cm) in the left testis and the patient was diagnosed with stage IIIB left testicular cancer. A left high orchidectomy was then performed, and pathological examination revealed embryonal carcinoma. The patient was started on a systemic chemotherapeutic (etoposide, ifosfamide and cisplatin; VIP) regimen. After the third chemotherapy session, metastases had completely disappeared, the serum levels of alpha-fetoprotein and human chorionic gonadotropin beta subunit had normalized and the dermatomyositis symptoms had improved. Cancer is known to be a trigger of dermatomyositis. This case illustrates the importance of palpation of the testes in young patients with dermatomyositis. |
| Databáze: | OpenAIRE |
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