Undiagnosed Systemic Mastocytosis Presenting as Postoperative Distributive Shock: A Case Report
| Autor: | Hartzell V. Schaff, Mark M. Smith, Juan G. Ripoll, Thomas B. Comfere, George D. Gilkey, Matthew J. Ritter, Matthew A. Warner |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Cardiopulmonary Bypass business.industry Biopsy Myocardial Bridging Disease Management General Medicine Shock Hemorrhagic medicine.disease Dermatology Article Proto-Oncogene Proteins c-kit Distributive shock Amino Acid Substitution Mastocytosis Systemic medicine Humans Systemic mastocytosis business Anaphylaxis Aged |
| Zdroj: | A A Pract |
| ISSN: | 2575-3126 |
| Popis: | Systemic mastocytosis (SM) is a rare clinical condition resulting from a clonal proliferation of abnormal mast cells. The clinical presentation may vary from mild cutaneous manifestations to aggressive systemic symptoms including intermittent episodes of anaphylaxis. We present a case of a 69-year-old male with abrupt and recurrent episodes of anaphylaxis with refractory distributive shock following cardiac surgery with cardiopulmonary bypass. Following a complex postoperative course, a bone marrow biopsy ultimately confirmed the diagnosis. Although rare, SM should be considered in the differential diagnosis of postoperative patients with unexplained and recurrent episodes of distributive shock. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|