Impact of Enterobacteriaceae bacteremia on survival in patients with hepatorenal failure
| Autor: | Mahmoud A. Soliman, Magee Saeed, Amin R. Soliman, Rabab Mahmoud Ahmed, A. M. Abdalla |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Creatinine
medicine.medical_specialty Cirrhosis medicine.diagnostic_test business.industry Liver cell lcsh:R lcsh:Medicine General Medicine medicine.disease Intensive care unit Gastroenterology law.invention chemistry.chemical_compound Liver disease chemistry Hepatorenal syndrome law Internal medicine Bacteremia medicine Blood culture business |
| Zdroj: | Saudi Journal of Kidney Diseases and Transplantation, Vol 29, Iss 6, Pp 1311-1319 (2018) |
| ISSN: | 1319-2442 |
| Popis: | Enterobacteriaceae are now the predominant pathogens isolated in patients with liver cell failure associated with bloodstream infections. We conducted a retrospective cohort study of patients who were admitted for the diagnosis of hepatorenal failure (HRF) between June 1999 and May 2008 to investigate the risk factors of Enterobacteriaceae bacteremia (EB). EB was defined as the isolation of an EB species from at least one blood culture within three months following diagnosis of HRF. Variables were collected from the medical records and analyzed in relation to EB. Twenty-four (32.5%) of the 73 patients developed EB. The origin of EB was abdominal in 21% of the patients, urinary in 12.5%, pulmonary in 16.5%, and primary in the remaining patients (50%). Two-thirds of EB occurred within 10 days following the development of HRF. The main pathogens were Escherichia coli (44%), Enterobacter species (20%) and Klebsiella pneumoniae (22%). Eighteen patients (75%) with EB died. Variables significantly associated with EB after multivariate analysis were a model for end-stage liver disease score >20 [odds ratio (OR): 2.84, P |
| Databáze: | OpenAIRE |
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