Reasons for failure to identify positive sentinel nodes in breast cancer patients with significant nodal involvement

Autor: S. C. Henzen-Logmans, Alexander M.M. Eggermont, Th. Wiggers, Marian B. E. Menke-Pluijmers, A.N. van Geel, C.J.H. van Eijck, A.Y. de Kanter
Přispěvatelé: Surgery
Jazyk: angličtina
Rok vydání: 2006
Předmět:
medicine.medical_treatment
MULTICENTER
extensive nodal involvement
GUIDELINES
EARLY-STAGE MELANOMA
Neoplasm Metastasis
Coloring Agents
Aged
80 and over
medicine.diagnostic_test
Ultrasound
General Medicine
Sentinel node
Middle Aged
Immunohistochemistry
failure
medicine.anatomical_structure
Oncology
Lymphatic Metastasis
BIOPSY
Keratins
Female
LYMPHOSCINTIGRAPHY
Adult
medicine.medical_specialty
FEASIBILITY
Biopsy
Fine-Needle
Breast Neoplasms
extra nodal growth
Breast cancer
breast cancer
SDG 3 - Good Health and Well-being
Predictive Value of Tests
Biopsy
Preoperative Care
medicine
Humans
Diagnostic Errors
Radionuclide Imaging
Technetium Tc 99m Aggregated Albumin
Ultrasonography
Interventional
Nodal involvement
Aged
BLUE-DYE
business.industry
Sentinel Lymph Node Biopsy
Axillary Lymph Node Dissection
medicine.disease
LYMPHADENECTOMY
Surgery
Axilla
sentinel node
Lymph Node Excision
EXPERIENCE
Lymphadenectomy
Lymph Nodes
Radiopharmaceuticals
business
Zdroj: European Journal of Surgical Oncology, 32(5), 498-501. ELSEVIER SCI LTD
European Journal of Surgical Oncology, 32(5), 498-501. W.B. Saunders
ISSN: 0748-7983
Popis: Aim: To analyse causes of failure of sentinel node (SN) procedures in breast cancer patients and assess the role of pre-operative ultrasound examination of the axilla. Methods: In 138 consecutive clinically node negative breast cancer patients with the primary tumour in situ a SN procedure with radiolabeled colloid and blue dye was performed. Radioactivity in the SN was scored as inadequate or adequate. The axillary lymph node dissection scored for number of involved nodes and presence of extranodal growth. Results: In 53/138 patients, the SN was positive for tumour. Full axillary node dissection revealed that 58/138 were node positive. So in five patients the SN failed to predict true nodal status. In 3/5, the radioactive ratio (SN vs background) was inadequate. All were found to have extensive nodal involvement. The radioactivity ratio was inadequate in 37/138 patients. This ratio was inadequate in 10 of 15 patients with ≥4 positive nodes and 27 of 123 in patients with 0-3 positive nodes (p
Databáze: OpenAIRE
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