Distribution of indole in tissues of dairy cattle, swine, and laying pullets
Autor: | G. R. Eisele |
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Rok vydání: | 1986 |
Předmět: |
Indoles
Meat Swine Eggs Health Toxicology and Mutagenesis Fowl Fractionation Toxicology Species Specificity medicine Animals Ecotoxicology Tissue Distribution Food science Dairy cattle Pollutant Indole test biology food and beverages General Medicine medicine.disease biology.organism_classification Pollution Hemolysis Milk Biochemistry Cattle Female Chickens Anaerobic exercise |
Zdroj: | Bulletin of Environmental Contamination and Toxicology. 37:246-252 |
ISSN: | 1432-0800 0007-4861 |
DOI: | 10.1007/bf01607757 |
Popis: | Indole is a colorless crystalline solid which has been isolated from coal tar fractionation. High concentrations of indole (which is a major ruminal fermentation product of L-tryptophan) in blood of cattle causes hemolysis, hemoglobinuria, and renal necrosis. An end product of anaerobic metabolism of the colonic flora, indole has also been examined as a marker in patients with unresected large bowel cancer or polyps. With the increased release of numerous chemical substances into the biosphere, careful assessment of the health effects of chronic exposure to pollutants must be made. Much of the body burden of animals will come from ingested feed and water, with the primary route of human exposure being the consumption of the contaminated meat, milk, and eggs. The purpose of this study was to obtain baseline data on the uptake and distribution of /sup 14/C-indole in dairy cattle, swine, and laying pullets and the retention of this chemical in consumable products such as milk, meat, and eggs. |
Databáze: | OpenAIRE |
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