Interleukin-1 levels in gingival crevicular fluid adjacent to restorations of calcium aluminate cement and resin composite
| Autor: | Jan W.V. van Dijken, Katarina Konradsson |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Aluminate medicine.medical_treatment Sialoglycoproteins Gingiva Dentistry chemistry.chemical_element Dental Cements Calcium Composite Resins Tooth Cervix Statistics Nonparametric chemistry.chemical_compound stomatognathic system Dental cement medicine Humans Aluminum Compounds Dental Restoration Permanent Aged Cement Aged 80 and over Enamel paint business.industry technology industry and agriculture Interleukin Receptors Interleukin-1 Gingival Crevicular Fluid Calcium Compounds Middle Aged Gingivitis Interleukin 1 Receptor Antagonist Protein Cross-Sectional Studies chemistry visual_art visual_art.visual_art_medium Periodontics Female business Dental restoration Interleukin-1 |
| Zdroj: | Journal of clinical periodontology. 32(5) |
| ISSN: | 0303-6979 |
| Popis: | The aim of this clinical study was to intra-individually compare Class V restorations of a calcium aluminate cement (CAC), resin composite and enamel with respect to the adjacent levels of interleukin (IL)-1alpha, IL-1beta and IL-1 receptor antagonist (IL-1ra) in gingival crevicular fluid (GCF). The hypothesis was that there are higher IL-1 levels adjacent to resin composite, compared with CAC and enamel.In 15 subjects, at least one set of two Class V restorations with subgingival margins, one CAC and one universal hybrid resin composite, and one control surface of enamel were included. In a cross-sectional study and on days 0, 3 and 7 of an experimental gingivitis study, GCFs were collected with Periopaper for 30 s. The GCF concentrations of IL-1alpha, IL-1beta and IL-1ra were quantified with enzyme linked immunosorbent assays.Neither the cross-sectional study nor the experimental gingivitis study showed any significant differences in the levels of IL-1alpha, IL-1beta and IL-1ra between CAC, resin composite and enamel sites (p0.05). In the cross-sectional study, low IL-1 concentrations were observed. The IL-1 levels increased significantly during the experimental gingivitis.Regardless of CAC or resin composite, the restorations per se did not affect the GCF levels of IL-1 and IL-1ra, neither at healthy gingiva, nor at initiation of plaque-related gingival inflammation. |
| Databáze: | OpenAIRE |
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