Supplementary Figures 1-2, Supplementary Tables 1-3 from Identification of CCR2 and CD180 as Robust Pharmacodynamic Tumor and Blood Biomarkers for Clinical Use with BRD4/BET Inhibitors

Autor: Huawei Chen, J. Carl Barrett, Maureen Hattersley, Austin Dulak, Philip Petteruti, Greg O'Connor, Tammie C. Yeh
Rok vydání: 2023
DOI: 10.1158/1078-0432.22465697.v1
Popis: Figure S1: Downregulation of CCR2, CD180, MYC and upregulation of HEXIM1 mRNAs by AZD5153 in cells can be detected at 4h; Figure S2: Other BRD4/BET compounds can also downregulate CCR2 and CD180 mRNAs in hematological tumor cell lines; Supplementary Table 1: Description of cell lines used in the RNAseq study; Supplementary Table 2: Information on qPCR assays used in these studies; Supplementary Table 3: More detailed information for each healthy volunteer and patient sample.
Databáze: OpenAIRE