Anatomy and White Matter Connections of the Lingual Gyrus and Cuneus
| Autor: | Ali H. Palejwala, Kyle P. O'Connor, Andrew K. Conner, Nicholas B. Dadario, Robert G. Briggs, Michael E. Sughrue, Daniel L. O'Donoghue, Isabella M. Young |
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| Rok vydání: | 2021 |
| Předmět: |
Cuneus
Temporal lobe Lingual gyrus 03 medical and health sciences 0302 clinical medicine Neural Pathways Fasciculus Connectome Humans Medicine Inferior longitudinal fasciculus biology business.industry Anatomy biology.organism_classification White Matter Diffusion Tensor Imaging medicine.anatomical_structure 030220 oncology & carcinogenesis Surgery Occipital Lobe Neurology (clinical) Verbal memory business Occipital lobe 030217 neurology & neurosurgery Tractography |
| Zdroj: | World Neurosurgery. 151:e426-e437 |
| ISSN: | 1878-8750 |
| DOI: | 10.1016/j.wneu.2021.04.050 |
| Popis: | Background The medial occipital lobe, composed of the lingual gyrus and cuneus, is necessary for both basic and higher level visual processing. It is also known to facilitate cross-modal, nonvisual functions, such as linguistic processing and verbal memory, after the loss of the visual senses. A detailed cortical model elucidating the white matter connectivity associated with this area could improve our understanding of the interacting brain networks that underlie complex human processes and postoperative outcomes related to vision and language. Methods Generalized q-sampling imaging tractography, validated by gross anatomic dissection for qualitative visual agreement, was performed on 10 healthy adult controls obtained from the Human Connectome Project. Results Major white matter connections were identified by tractography and validated by gross dissection, which connected the medial occipital lobe with itself and the adjacent cortices, especially the temporal lobe. The short- and long-range connections identified consisted mainly of U-shaped association fibers, intracuneal fibers, and inferior fronto-occipital fasciculus, inferior longitudinal fasciculus, middle longitudinal fasciculus, and lingual–fusiform connections. Conclusions The medial occipital lobe is an extremely interconnected system, supporting its ability to perform coordinated basic visual processing, but also serves as a center for many long-range association fibers, supporting its importance in nonvisual functions, such as language and memory. The presented data represent clinically actionable anatomic information that can be used in multimodal navigation of white matter lesions in the medial occipital lobe to prevent neurologic deficits and improve patients' quality of life after cerebral surgery. |
| Databáze: | OpenAIRE |
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