Distribution of α2Hs Glycoprotein in Pathological Human Dentins
| Autor: | Junko Kindaichi, Hitoyata Shimokawa, Satoshi Sasaki, Michiko Suzuki, Keiji Moriyama, Yuzo Takagi |
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| Rok vydání: | 1994 |
| Předmět: |
Male
Adolescent alpha-2-HS-Glycoprotein Alpha (ethology) Biochemistry stomatognathic system Rheumatology Reference Values Dentin medicine Humans Tissue Distribution Orthopedics and Sports Medicine Child Molecular Biology chemistry.chemical_classification Osmolar Concentration Blood Proteins Cell Biology medicine.disease Immunohistochemistry Molecular biology stomatognathic diseases medicine.anatomical_structure Dentinal Tubule Odontoblast chemistry Tooth Diseases Child Preschool Female Glycoprotein alpha-2-HS-glycoprotein Calcification |
| Zdroj: | Connective Tissue Research. 30:309-321 |
| ISSN: | 1607-8438 0300-8207 |
| DOI: | 10.3109/03008209409015045 |
| Popis: | The concentration and distribution of alpha 2HS glycoprotein in teeth from patients with heritable dentin disorders were examined utilizing immunological techniques. ELISA for the quantitative determination showed lower concentrations of alpha 2HS glycoprotein in dentins of patients with heritable disorders than in the control; some cases contained very low and others intermediate concentrations. Immunohistochemical findings indicated that the concentration of this protein was correlated to the regularity of the dentinal tubules. This result suggests that alpha 2HS glycoprotein is incorporated into dentin in concomitance with the development of the dentinal tubule, especially with the deposition of peritubular dentin. Incorporation of this protein into dentin is thought to involve the function of odontoblasts. |
| Databáze: | OpenAIRE |
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