Reproducibility of computer-aided volumetry of artificial small pulmonary nodules in ex vivo porcine lungs
| Autor: | Gerhard Kohl, Thomas Jahnke, Jürgen Biederer, Hendrik Bolte, S. Freitag, Christian Riedel, Martin Heller, Nevin Inan |
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| Rok vydání: | 2005 |
| Předmět: |
Lung Neoplasms
Swine Slice thickness Computed tomography In Vitro Techniques Imaging phantom Statistics Nonparametric Medicine Animals Radiology Nuclear Medicine and imaging Degree of certainty Reproducibility Analysis of Variance medicine.diagnostic_test business.industry Phantoms Imaging Reproducibility of Results Solitary Pulmonary Nodule Nodule (medicine) General Medicine Radiographic Image Interpretation Computer-Assisted medicine.symptom business Nuclear medicine Tomography X-Ray Computed Ex vivo Software |
| Zdroj: | Investigative radiology. 41(1) |
| ISSN: | 0020-9996 |
| Popis: | Objective: The main purpose of this study was to investigate the reproducibility of computed tomography (CT)-based volumetric measurements of small pulmonary nodules. Methods: We implanted 70 artificial pulmonary nodules in 5 ex vivo porcine lungs in a dedicated chest phantom. The lungs were scanned 5 times consecutively with multislice-CT (collimation 16 X 0.75 mm, slice thickness 1 mm, reconstruction increment 0.7 mm). A commercial software package was used for lesion volumetry. The authors differentiated between intrascan reproducibility, interscan reproducibility, and results from semiautomatic and postprocessed volumetry. Results: Analysis of intrascan reproducibility revealed a mean variation coefficient of 6.2% for semiautomatic volumetry and of 0.7% for human adapted volumetry. For interscan reproducibility a mean variation coefficient of 9.2% and for human adapted volumetry a mean of 3.7% was detected. Conclusion: The presented volumetry software showed a high reproducibility that can be expected to detect nodule growth with a high degree of certainty. |
| Databáze: | OpenAIRE |
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