The Anti-human CD21 Antibody, BU33, Identifies Equine B Cells
| Autor: | S. Mayall, E.M. Siedek, A.S. Hamblin |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
medicine.drug_class
Complement receptor 2 chemical and pharmacologic phenomena Spleen Monoclonal antibody Epitope Immunophenotyping Pathology and Forensic Medicine medicine Animals Humans Horses Fluorescent Antibody Technique Indirect Receptor B-Lymphocytes General Veterinary biology Antibodies Monoclonal Flow Cytometry medicine.anatomical_structure Immunology biology.protein Receptors Complement 3d Lymph Nodes Lymph Antibody Biomarkers |
| Zdroj: | Journal of Comparative Pathology. 124:83-87 |
| ISSN: | 0021-9975 |
| DOI: | 10.1053/jcpa.2000.0425 |
| Popis: | The number of antibodies for identifying equine B cells is small and the number that react with well-defined epitopes even smaller. The monoclonal antibody, BU33, which is directed against human CD21 (Complement Receptor 2; CR2) was shown to identify (1) follicular lymphocytes in the lymph nodes and spleen of three horses, and (2) a mean of 18 +/- 6% (SEM) of peripheral blood lymphocytes from 10 horses. These findings indicate that the antibody identifies equine B cells and possibly equine CR2 or a related molecule. This study adds to the reagents available for equine research and diagnostic pathology. |
| Databáze: | OpenAIRE |
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