The impact of survey nonresponse bias on conclusions drawn from a mammography intervention trial

Autor: Jonathan S. Slater, Melissa R. Partin, Annette Bar-Cohen, Mary Winnett, Lee S. Caplan, Michael E. Malone
Rok vydání: 2003
Předmět:
Zdroj: Journal of clinical epidemiology. 56(9)
ISSN: 0895-4356
Popis: Background and objective This study demonstrates the impact of survey nonresponse bias on conclusions from a mammography trial targeting a disadvantaged population. Methods The trial randomized 1558 women to three interventions designed to promote repeat mammography: mailed reminder (minimum group); mailed thank-you card, patient newsletters, and reminder (maximum group); and no mailings (control group). The primary outcome, repeat mammogram within 15 months, was assessed from administrative and phone survey data. Results Administrative estimates revealed a statistically significant difference of 7% between the maximum and control groups on the primary outcome. Survey estimates (response rate 80%) revealed no significant differences. The differences by data source were traced to a survey nonresponse bias. There was a statistically significant difference of 16% between the maximum and control groups among survey nonrespondents for the primary outcome, but there were no differences among survey respondents. Conclusion The findings reiterate that even a low survey nonresponse rate can bias study conclusions and suggest studies targeting disadvantaged populations should avoid relying solely on survey data for outcome analyses.
Databáze: OpenAIRE