Pressure dependence of protein dynamics investigated using elastic and quasielastic neutron scattering
| Autor: | Antonio Deriu, M.T. Di Bari, Nicola Rosato, A. Filabozzi, A. Di Venere, Carla Andreani |
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| Rok vydání: | 2005 |
| Předmět: |
Proton
Proton dynamics Nuclear Theory Neutron scattering Pressure effects Protein dynamics Molecular physics General Materials Science Nuclear Experiment Monomeric proteins Elastic scattering Quasielastic neutron scattering Chemistry Settore FIS/01 - Fisica Sperimentale Dynamics (mechanics) Proteins Condensed Matter Physics Elasticity Crystallography Volume (thermodynamics) Protons Bar (unit) |
| Zdroj: | Journal of Physics: Condensed Matter. 17:S3101-S3109 |
| ISSN: | 1361-648X 0953-8984 |
| DOI: | 10.1088/0953-8984/17/40/013 |
| Popis: | We present here a study of the dynamics of two monomeric proteins, trypsin and lysozyme, by means of elastic and quasielastic neutron scattering under medium-to-high pressure conditions (1-1200 bar). The internal motions as probed from the average proton dynamics in the 100 ps timescale have a confined diffusive nature. On increasing the pressure up to 1200 bar the confinement volume is almost unaffected, while the fraction of protons involved is slightly decreased. |
| Databáze: | OpenAIRE |
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