Influenza in Three Patients with Human Immunodeficiency Virus Infection
| Autor: | Kyoji Kakuda, Yong Chong, Seizaburo Kashiwagi, Iwao Ariyama, Jun Hayashi, Kohei Hirotsu, Shigeki Nabeshima |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Male Orthomyxoviridae HIV Infections CD8-Positive T-Lymphocytes medicine.disease_cause Virus Acquired immunodeficiency syndrome (AIDS) Antiretroviral Therapy Highly Active Influenza Human Internal Medicine medicine Influenza A virus Humans Lymphocyte Count Sida AIDS-Related Opportunistic Infections biology business.industry virus diseases General Medicine medicine.disease biology.organism_classification Virology CD4 Lymphocyte Count Influenza Vaccines Lentivirus Immunology RNA Viral Bronchitis Female Viral disease business |
| Zdroj: | Internal Medicine. 39:592-597 |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.39.592 |
| Popis: | Three Japanese outpatients with human immunodeficiency virus (HIV) infection on anti-retroviral therapy showed evidence of influenza in January 1999. CD4+ T cell counts of these patients prior to the diagnosis of influenza were 72, 248, and 152/mm3, and HIV RNA levels were 19,953, 1,259, and 1,585 copies/ml, respectively. Fever continued 4 to 5 days with no severe complications. One patient showed post-influenzal bronchitis which was effectively treated by antibiotics. None of these patients showed increased serum HIV RNA levels during and after influenza, however, in one patient, a transient reduction of CD4+ and CD8+ cells was seen during the active phase of influenza. Although symptoms of influenza in HIV carriers are generally mild and similar to those in healthy adults, careful follow-up is needed as symptoms of influenza in some HIV-infected patients can be prolonged and serious. |
| Databáze: | OpenAIRE |
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