Electroencephalography-based neurofeedback as treatment for post-traumatic stress disorder: A systematic review and meta-analysis
| Autor: | Iris Sarajlic Vukovic, Mikael Svensson, Olof Wrede, Tomas Larson, Ann-Catrin Ekelund, Constanze Wartenberg, Steinn Steingrimsson, Gorana Bilonic, Susanne Bernhardsson, Ida Stadig |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Waiting Lists medicine.medical_treatment Biofeedback Review law.invention Stress Disorders Post-Traumatic Quality of life Randomized controlled trial systematic review law medicine Humans EEG business.industry Traumatic stress Electroencephalography neurofeedback Confidence interval Psychiatry and Mental health Strictly standardized mean difference Meta-analysis Physical therapy Quality of Life post-traumatic stress disorder Neurofeedback business Self-Injurious Behavior |
| Zdroj: | European Psychiatry |
| ISSN: | 1778-3585 0924-9338 |
| Popis: | Background Post-traumatic stress disorder (PTSD) is debilitating for patients and society. There are a number of treatment methods albeit not all patients respond to these and an interesting method using electroencephalography-based neurofeedback (EEG-NF) has become more prominent in recent years. This systematic review aimed to assess whether EEG-NF, compared with sham NF, other treatment, or no treatment, is effective for PTSD. Primary outcomes were self-harm, PTSD symptoms, level of functioning and health-related quality of life. Methods Systematic literature searches for randomized controlled trials (RCTs) were conducted in six databases. Random effects meta-analysis was performed. Certainty of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation. Results Four RCTs were included (123 participants). Suicidal thoughts were significantly reduced after EEG-NF compared with a waiting list in a small study. PTSD symptoms were assessed in all studies with different instruments. Results were consistently in favor of EEG-NF with large effect sizes (standardized mean difference −2.30 (95% confidence interval: −4.37 to −0.24). One study reported significantly improved level of executive functioning and one study a reduction in use of psychotropic medication. Complications were scarcely reported. Certainty of evidence was assessed as very low for the four assessed outcomes. Conclusions Based on four RCTs, with several study limitations and imprecision, it is uncertain whether EEG-NF reduces suicidal thoughts, PTSD symptoms, medication use, or improves function. Although all studies showed promising results, further studies are needed to increase the certainty of evidence. |
| Databáze: | OpenAIRE |
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