Complications in Neonates With Short Bowel Syndrome and Long-Term Parenteral Nutrition
| Autor: | Takeshi Yamanouchi, Sachiyo Suita, Masatoshi Nakamura, Miki Nagano, Kouji Masumoto |
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| Rok vydání: | 1999 |
| Předmět: |
Male
Short Bowel Syndrome Parenteral Nutrition medicine.medical_specialty Micronutrient deficiency 030309 nutrition & dietetics Medicine (miscellaneous) Gestational Age Disease Enteral administration Gastroenterology 03 medical and health sciences 0302 clinical medicine Cholestasis Internal medicine medicine Humans 0303 health sciences Nutrition and Dietetics business.industry Infant Newborn Nutritional Requirements Prognosis medicine.disease Micronutrient Short bowel syndrome Trace Elements Parenteral nutrition Female 030211 gastroenterology & hepatology business Complication |
| Zdroj: | Journal of Parenteral and Enteral Nutrition. 23:S106-S109 |
| ISSN: | 1941-2444 0148-6071 |
| DOI: | 10.1177/014860719902300526 |
| Popis: | Background: Because of advances in parenteral nutrition (PN), the prognosis for patients with short bowel syndrome (SBS) has recently shown great improvement. Even infants with a small bowel measuring only 20 cm either with or without an ileocoecal valve can now survive. However, because of the increased periods of PN, severe complications associated with PN have been observed. Patients and Methods: We analyzed 17 patients with SBS treated by long-term PN to investigate the complications of PN, particularly hepatic dysfunction, micronutrient deficiency, and intoxication. Results: Eleven of 17 patients (64.7%) had hepatic dysfunction, mostly cholestasis. The main causes of hepatic dysfunction were loss of enteral feeding and infections. Regarding the complications of the micronutrients, zinc and copper deficiencies have been observed less often because of trace element supplements. However, manganese deposition, especially in the basal ganglia, was recognized in one patient. Conclusions: We therefore need to pay more attention to these problems when treating this disease in order to improve the overall prognosis significantly. |
| Databáze: | OpenAIRE |
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