Recurrent Ventricular Tachycardia Due to Pentamidine-Induced Cardiotoxicity
Autor: | Te-Chuan Chou, Robert J. Toltzis, Mark R. Bibler, Patricia A. Wade |
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Rok vydání: | 1988 |
Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Electrical alternans Pentamidine Isethionate Amidines Torsades de pointes Critical Care and Intensive Care Medicine Ventricular tachycardia QT interval Electrocardiography Recurrence Tachycardia Internal medicine medicine Humans cardiovascular diseases Pentamidine Acquired Immunodeficiency Syndrome Cardiotoxicity business.industry Pneumonia Pneumocystis Heart medicine.disease Pneumonia Anesthesia Cardiology Cardiology and Cardiovascular Medicine business medicine.drug |
Zdroj: | Chest. 94:1303-1306 |
ISSN: | 0012-3692 |
DOI: | 10.1378/chest.94.6.1303 |
Popis: | Although pentamidine isethionate is effective in the treatment of Pneumocystis carinii pneumonia, it frequently causes serious adverse reactions. We report a case of reversible pentamidine-induced cardiotoxicity, characterized electrocardiographically by prolongation of the QT interval, T-wave inversion, and electrical alternans of the U-wave. In addition, the patient had repeated episodes of ventricular tachycardia that culminated in torsades de pointes. Our case re-emphasizes the need for close patient monitoring during pentamidine therapy. Chest 1988; 94:1303-06 |
Databáze: | OpenAIRE |
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