Recurrent Ventricular Tachycardia Due to Pentamidine-Induced Cardiotoxicity

Autor: Te-Chuan Chou, Robert J. Toltzis, Mark R. Bibler, Patricia A. Wade
Rok vydání: 1988
Předmět:
Zdroj: Chest. 94:1303-1306
ISSN: 0012-3692
DOI: 10.1378/chest.94.6.1303
Popis: Although pentamidine isethionate is effective in the treatment of Pneumocystis carinii pneumonia, it frequently causes serious adverse reactions. We report a case of reversible pentamidine-induced cardiotoxicity, characterized electrocardiographically by prolongation of the QT interval, T-wave inversion, and electrical alternans of the U-wave. In addition, the patient had repeated episodes of ventricular tachycardia that culminated in torsades de pointes. Our case re-emphasizes the need for close patient monitoring during pentamidine therapy. Chest 1988; 94:1303-06
Databáze: OpenAIRE