In Vitro Evaluation of Dentin Tubule Occlusion for Novel Calcium Lactate Phosphate (CLP) Paste
Autor: | Hsin Tai Hu, Dian Yu Ji, Sheng Yang Lee, Nai Chia Teng, Pei Chi Huang, Jen Chang Yang, Chen Feng Ma, Liang Yu Chang, Sung Chih Hsieh |
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Rok vydání: | 2017 |
Předmět: |
Saliva
calcium lactate phosphate (CLP) Materials science chemistry.chemical_element Mineralogy desensitizing agent Calcium lcsh:Technology Article 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine stomatognathic system Dentin medicine General Materials Science lcsh:Microscopy lcsh:QC120-168.85 lcsh:QH201-278.5 lcsh:T dentin hypersensitivity 030206 dentistry medicine.disease Lactic acid stomatognathic diseases medicine.anatomical_structure Tubule Dentinal Tubule Distilled water chemistry lcsh:TA1-2040 Dentin hypersensitivity lcsh:Descriptive and experimental mechanics lcsh:Electrical engineering. Electronics. Nuclear engineering lcsh:Engineering (General). Civil engineering (General) lcsh:TK1-9971 030217 neurology & neurosurgery Biomedical engineering |
Zdroj: | Materials, Vol 10, Iss 3, p 228 (2017) Materials; Volume 10; Issue 3; Pages: 228 Materials |
ISSN: | 1996-1944 |
DOI: | 10.3390/ma10030228 |
Popis: | Introduction: The objective of this in vitro study is to evaluate the effective and long-term occlusion of dentinal tubules using a novel calcium lactate phosphate (CLP) based desensitizing agent. Methods: Dentin disks (n = 9) were pre-etched using 1 M lactic acid for 30 s and individually treated with Colgate® Pro-Relief™ paste, CLP paste, and double distilled water (ddH2O) by a rubber-cupped handpiece. Dentin disks were analyzed under optical micrographs for pre-treatment, directly after treatment, and 14 days post-treatment. One-way ANOVA and post-hoc Tukey’s test were used to determine whether there were any statistically significant differences in dentinal tubule diameter. Results: A significant decrease occurred in the mean tubule diameter for dentin disks treated with CLP paste. A decrease was observed from 3.52 ± 0.83 µm to 2.62 ± 0.42 µm right after treatment, further decreasing to 1.71 ± 0.45 µm after immersion in artificial saliva for 14 days (p < 0.05). Conclusions: The results suggest that the CLP based desensitizing paste has remineralization properties and provides instant and lasting effectiveness in dentinal tubule occlusion. |
Databáze: | OpenAIRE |
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