Immunotherapy in metastatic renal cell carcinoma
| Autor: | K. Rohrmann, Michael Siebels, Christian G. Stief, N. Haseke, Michael Staehler, Alexander Bachmann |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Nephrology
Antimetabolites Antineoplastic medicine.medical_specialty medicine.drug_class Urology medicine.medical_treatment Antineoplastic Agents Antimetabolite Metastasis Renal cell carcinoma Internal medicine Antineoplastic Combined Chemotherapy Protocols medicine Carcinoma Humans Carcinoma Renal Cell Chemotherapy business.industry Interferon-alpha Immunotherapy medicine.disease Kidney Neoplasms Immunology Cancer research Interleukin-2 Fluorouracil business Kidney cancer |
| Zdroj: | World Journal of Urology. 23:196-201 |
| ISSN: | 1433-8726 0724-4983 |
| Popis: | Metastatic renal cell carcinoma has a poor prognosis. Conventional therapies such as chemotherapy, radiation or hormonal treatment have hardly any effect on the progression of this disease. As renal cell carcinoma seems to be an immunogenic tumor, several immunotherapeutic approaches with different response rates have been developed since the early 1990s. We present an overview of various immunotherapeutic approaches such as cytokine-based regimes, with and without different cytotoxic chemotherapy, of metastatic renal cell carcinoma. In addition, local therapies (e.g. inhalation of interleukin-2) are reviewed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink