Evaluation of a Commercial PCR Kit for Diagnosis of Cytomegalovirus Infection of the Central Nervous System

Autor:	Guan-Yung Cai, Christopher M. Long, Vince Tevere, Rita Sun, Adriana Weinberg, Debbie Spiers
Jazyk:	angličtina
Rok vydání:	1998
Předmět:	Microbiology (medical) Human cytomegalovirus Congenital cytomegalovirus infection Cytomegalovirus medicine.disease_cause Polymerase Chain Reaction Sensitivity and Specificity Virus Herpesviridae law.invention Central nervous system disease Central Nervous System Infections Betaherpesvirinae law Virology medicine Humans Polymerase chain reaction Cerebrospinal Fluid DNA Primers biology Base Sequence virus diseases biology.organism_classification medicine.disease Evaluation Studies as Topic Immunology Cytomegalovirus Infections DNA Viral Viral disease
Popis:	We evaluated the AMPLICOR cytomegalovirus (CMV) PCR kit for the diagnosis of neurologic CMV infections on 43 positive and 112 negative archived cerebrospinal fluid specimens originally tested by an in-house PCR method. The AMPLICOR kit showed sensitivity and specificity of 95 and 100%, respectively, versus the home-grown assay, indicating its utility in this clinical setting.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314b28553cbf06eb2cacbbbaf1e0b326 https://europepmc.org/articles/PMC105337/ Zobrazit plný text záznamu