Oral intravascular fasciitis: a rare maxillofacial lesion
| Autor: | Amir Shuster, Yaniv Dagan, Josephine Issakov, Vadim Reiser, Michael Alterman, Ilana Kaplan, Benjamin Shlomi, Shlomi Kleinman |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
CD31
Pathology medicine.medical_specialty CD34 Nodular fasciitis Pathology and Forensic Medicine Diagnosis Differential Lesion medicine Humans Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Fasciitis business.industry Sarcoma Arteries Anatomy Middle Aged medicine.disease Facial Asymmetry Immunohistochemistry Female Surgery Oral Surgery Differential diagnosis medicine.symptom Mouth Diseases business |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 114:e40-e44 |
| ISSN: | 2212-4403 |
| DOI: | 10.1016/j.oooo.2012.03.027 |
| Popis: | Nodular fasciitis is a benign non-neoplastic myofibroblastic proliferation, involving the head in 7% to 20% of cases. Intravascular fasciitis (IVF) is a rare variant, with a unique intravascular growth pattern. Only 4 maxillofacial cases have been previously reported. We describe a 58-year-old woman with a rapidly growing, hard, mobile buccal submucosal swelling. CT scans identified a well-defined, 1.7-cm isodense lesion, located between the mental foramen and masseter muscle, which was excised under general anesthesia. A well-defined cellular nodular mass was composed of bland spindle cells, in a densely vascularized, focally myxoid matrix, involving an arterial lumen, and extending into adjacent tissues. Mitoses were rare. Immunohistochemistry was positive for smooth muscle actin, negative for keratins, S-100, epithelial membrane antigen, caldesmon, p53 and Alk. CD31 and CD34 were positive only in the vascular component, supporting the diagnosis of intravascular fasciitis. |
| Databáze: | OpenAIRE |
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