Maximum standardised uptake value of quantitative bone SPECT/CT in patients with medial compartment osteoarthritis of the knee
| Autor: | Won Woo Lee, Tae Kyun Kim, Young So, Yusuhn Kang, J. Kim, Sook-Kyung Lee, Hey-Jin Lee |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Knee Joint Osteoarthritis Technetium Tc 99m Medronate Bone and Bones 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Humans Medicine Radiology Nuclear Medicine and imaging In patient Arthrography Compartment (pharmacokinetics) Retrospective Studies Tomography Emission-Computed Single-Photon 030203 arthritis & rheumatology medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine Middle Aged Osteoarthritis Knee medicine.disease Magnetic Resonance Imaging Tracer uptake Female Plain radiographs Radiology Tomography Radiopharmaceuticals business Nuclear medicine |
| Zdroj: | Clinical Radiology. 72:580-589 |
| ISSN: | 0009-9260 |
| DOI: | 10.1016/j.crad.2017.03.009 |
| Popis: | To evaluate the correlation between the maximum standardised uptake value (SUVmax) from bone single-photon-emission computed tomography/computed tomography (SPECT/CT) and other imaging parameters for medial compartment osteoarthritis (OA) of the knee.Patients (n=26; male:female=2:24; age, 55.3±5.8 years) underwent quantitative knee SPECT/CT using technetium-99m (Tc-99m) hydroxymethylene diphosphonate (HDP) before surgical operation for medial OA of the knee. SUVmax was calculated using dedicated quantitative software. Visual grades of tracer uptake on bone SPECT/CT and Kellgren-Lawrence (KL) OA scores on plain radiographs were assessed using a five-point scale. Magnetic resonance imaging (MRI) scores (n=22) and patient symptom scores were also assessed.The operated knees (n=34) had a greater SUVmax than the non-operated knees (n=18) in the medial compartment (14.1±6.1 versus 5.3±4.4, p0.0001). In the medial compartment, the SUVmax was significantly correlated with SPECT/CT visual grades (rho=0.794, p0.0001), KL scores (rho=0.703, p0.0001), and MRI scores (rho=0.714-0.808, p≤0.0002); however, SUVmax and other imaging parameters were not correlated with patient symptom scores (p0.05).The SUVmax of quantitative bone SPECT/CT was highly correlated with traditional imaging parameters for medial compartment OA severity of the knee. Quantitative bone SPECT/CT is a promising imaging technique for the objective assessment of knee OA. |
| Databáze: | OpenAIRE |
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