Neurological manifestations and implications of COVID-19 pandemic
| Autor: | Amrou Sarraj, Sotirios Tsiodras, Martin Köhrmann, Urs Fischer, Vivek Sharma, Amanda C. Chan, Andrei V. Alexandrov, Konstantinos Voumvourakis, Charlotte Cordonnier, Lina Palaiodimou, Georgios Tsivgoulis, Valeria Caso, Peter J. Kelly, Peter D. Schellinger, Nikolaos Grigoriadis, Carlos A. Molina, Ramin Zand, Aristeidis H. Katsanos |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Encephalopathy Medizin Review healthcare impact medicine.disease_cause lcsh:RC346-429 03 medical and health sciences 0302 clinical medicine Hyposmia Pandemic Medicine 030212 general & internal medicine Intensive care medicine 610 Medicine & health lcsh:Neurology. Diseases of the nervous system Coronavirus Pharmacology SARS-CoV-2 business.industry Hypogeusia COVID-19 medicine.disease Comorbidity Neurology neurological manifestations Neurology (clinical) medicine.symptom business cerebrovascular diseases 030217 neurology & neurosurgery Encephalitis Cohort study |
| Zdroj: | Therapeutic Advances in Neurological Disorders Therapeutic Advances in Neurological Disorders, Vol 13 (2020) |
| DOI: | 10.7892/boris.147356 |
| Popis: | The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China and rapidly spread worldwide, with a vast majority of confirmed cases presenting with respiratory symptoms. Potential neurological manifestations and their pathophysiological mechanisms have not been thoroughly established. In this narrative review, we sought to present the neurological manifestations associated with coronavirus disease 2019 (COVID-19). Case reports, case series, editorials, reviews, case-control and cohort studies were evaluated, and relevant information was abstracted. Various reports of neurological manifestations of previous coronavirus epidemics provide a roadmap regarding potential neurological complications of COVID-19, due to many shared characteristics between these viruses and SARS-CoV-2. Studies from the current pandemic are accumulating and report COVID-19 patients presenting with dizziness, headache, myalgias, hypogeusia and hyposmia, but also with more serious manifestations including polyneuropathy, myositis, cerebrovascular diseases, encephalitis and encephalopathy. However, discrimination between causal relationship and incidental comorbidity is often difficult. Severe COVID-19 shares common risk factors with cerebrovascular diseases, and it is currently unclear whether the infection per se represents an independent stroke risk factor. Regardless of any direct or indirect neurological manifestations, the COVID-19 pandemic has a huge impact on the management of neurological patients, whether infected or not. In particular, the majority of stroke services worldwide have been negatively influenced in terms of care delivery and fear to access healthcare services. The effect on healthcare quality in the field of other neurological diseases is additionally evaluated. |
| Databáze: | OpenAIRE |
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