Bilateral lesions of the paraventricular hypothalamic nucleus disrupt nursing behavior in rabbits
| Autor: | Raúl Aguilar-Roblero, Miguel Domínguez, Gabriela González-Mariscal |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Litter (animal)
endocrine system Kainic acid Paraventricular hypothalamic nucleus Body weight Eating 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Nursing Lactation medicine Animals 0501 psychology and cognitive sciences 050102 behavioral science & comparative psychology Circadian rhythm Maternal Behavior Kainic Acid business.industry General Neuroscience Body Weight digestive oral and skin physiology 05 social sciences Actigraphy Circadian Rhythm medicine.anatomical_structure nervous system chemistry Oxytocin Female Rabbits business Nucleus hormones hormone substitutes and hormone antagonists 030217 neurology & neurosurgery Paraventricular Hypothalamic Nucleus medicine.drug |
| Zdroj: | European Journal of Neuroscience. 46:2133-2140 |
| ISSN: | 1460-9568 0953-816X |
| DOI: | 10.1111/ejn.13656 |
| Popis: | Doe rabbits nurse the litter only once a day, for around 3 min, with circa 24-h periodicity. To explore the participation of the paraventricular nucleus (PVN) in regulating this behavior, we lesioned it bilaterally with kainic acid on lactation day 7. Bilateral lesions, comprising less than 50% of the total PVN volume, abolished nursing behavior (4/8 does) or severely disrupted its normal periodicity (4/8 does). In the latter case, duration of nursing bouts was normal. Body weight, food and water intake were not significantly affected by bilateral PVN lesions. Unilateral lesions of the PVN or lesions located outside this nucleus did not significantly alter nursing periodicity or any other behavioral parameter. Results indicate an important role of the PVN for (i) maintaining maternal behavior, and (ii) the periodic display of nursing across lactation in rabbits. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
| Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |