Case Report: Molecular Detection of Dirofilaria repens in an Italian Patient after a Stay in Tanzania

Autor:	Maria Luisa Scarasciulli, Nicola Pugliese, Donato Antonio Raele, Ilaria Vasco, Giovanna La Salandra, Maria Assunta Cafiero, Gianfranco LaBella, Agata Calvario
Rok vydání:	2021
Předmět:	Doxycycline medicine.medical_specialty Acanthocheilonema viteae biology business.industry Articles biology.organism_classification Repens Gastroenterology Dirofilaria repens Infectious Diseases Tanzania Virology Internal medicine parasitic diseases Medicine Parasitology business medicine.drug
Zdroj:	The American Journal of Tropical Medicine and Hygiene
ISSN:	1476-1645 0002-9637
Popis:	A 35-year-old man was admitted to a hospital in the south of Italy because of a periocular nodule and subpalpebral edema. The patient reported having been stayed in Tanzania five months before. Hematologic parameters were within the normality range, the Acanthocheilonema viteae ELISA did not detect significant levels of antifilarial IgG, and no further symptoms were described. The surgical inspection of the nodule led to the isolation of two filarioid parasites, identified as Dirofilaria repens by scanning electron microscope (SEM), and then by molecular assays. Knott’s test did not reveal microfilaremia, whereas loop-mediated isothermal amplification and PCR detected D. repens DNA. The patient was treated with doxycycline, and he was found no more positive at the follow-up.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3131a30fa9773deec4cd82b87af51bc6 https://doi.org/10.4269/ajtmh.20-1360 Zobrazit plný text záznamu