| Autor: |
Yang, Feng, Hu, Anpei, Guo, Yanhua, Wang, Jianqun, Li, Dan, Wang, Xiaojing, Jin, Shikai, Yuan, Boling, Cai, Shuang, Zhou, Yi, Li, Qilan, Chen, Guo, Gao, Haiyang, Zheng, Liduan, Tong, Qiangsong |
| Rok vydání: |
2021 |
| DOI: |
10.6084/m9.figshare.16689924.v1 |
| Popis: |
Additional file 1: Fig. S1. Coding ability of ecircCUX1 in NB. Fig. S2. Expression profiles and roles of ecircCUX1-encoded p113. Fig. S3. Effects of ecircCUX1 or p113 on mitochondrial mass and structure in NB cells. Fig. S4. ecircCUX1 promotes fatty acid oxidation and growth of NB via encoding p113. Fig. S5. ecircCUX1 facilitates mitochondrial complex I activity and aggressiveness of NB in vivo. Fig. S6. Interaction of p113 with ZRF1 and BRD4 in NB cells. Fig. S7. ecircCUX1 facilitates expression of ALDH3A1, NDUFA1, or NDUFAF5 in NB cells. Fig. S8. ecircCUX1 reduces peroxidated lipids and increases mitochondrial membrane potential via ZRF1 or BRD4 in NB cells. Fig. S9. ZRF1 promotes mitochondrial complex I activity, growth, and aggressiveness of NB cells via target genes. Fig. S10. Effects of inhibitory peptides blocking p113-ZRF1 interaction. Fig. S11. ZIP-12 inhibits viabilities, growth, invasion, and metastasis of NB cells. Fig. S12. Kaplan-Meier curves of ZRF1 and BRD4 in multiple cancers. Table S1. Primer sets used for RT-PCR, qPCR and ChIP. Table S2. Oligonucleotide sets used for constructs. Table S3. Oligonucleotide sets used for short hairpin RNAs and CRISPR-Cas9/dCas9. Table S4. Mass spectrometry analysis of proteins altered by serum deprivation. Table S5. p113 expression in human NB tissues. Table S6. Mass spectrometry analysis of proteins pulled down by p113 antibody. Table S7. Mass spectrometry analysis of proteins pulled down by Flag antibody. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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