Orientation of nucleosomes and linker DNA in calf thymus chromatin determined by photochemical dichroism

Autor:	Donald M. Crothers, Dipankar Sen, Sekhar Mitra
Rok vydání:	1984
Předmět:	Multidisciplinary Stereochemistry DNA Thymus Gland Dichroism Photochemistry Linker DNA Chromatin Nucleosomes chemistry.chemical_compound chemistry Nucleic acid Nucleic Acid Conformation Nucleosome Trioxsalen Derivative (chemistry) Psoralen
Zdroj:	Nature. 308:247-250
ISSN:	1476-4687 0028-0836
DOI:	10.1038/308247a0
Popis:	The dichroism for photochemical attachment of a psoralen derivative to Mg2+ -stabilized chromatin fibres is used to deduce the orientation of nucleosomal disks and linker DNA in the 30-nm fibre. The new technique of photochemical electric dichroism should have general applicability to problems of nucleic acid organization in cellular subunits and viruses.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312921e0155a0be3eb065a93f0ce66e2 https://doi.org/10.1038/308247a0 Zobrazit plný text záznamu