Dialysis Requiring Acute Kidney Injury in Acute Cerebrovascular Accident Hospitalizations
| Autor: | Achint Patel, Alexandre M. Benjo, Narender Annapureddy, Charuhas V. Thakar, Girish N. Nadkarni, Ioannis Konstantinidis, Shiv Kumar Agarwal, Abhimanyu Mahajan, Sunil Kamat |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Databases Factual medicine.medical_treatment Severity of Illness Index Brain Ischemia Sepsis Brain ischemia Renal Dialysis Risk Factors Atrial Fibrillation Epidemiology Odds Ratio Humans Medicine Hospital Mortality Renal Insufficiency Chronic Intensive care medicine Stroke Dialysis Aged Cerebral Hemorrhage Retrospective Studies Advanced and Specialized Nursing Intracerebral hemorrhage business.industry Incidence Acute kidney injury Atrial fibrillation Acute Kidney Injury Middle Aged medicine.disease Long-Term Care Patient Discharge United States Hospitalization Hypertension Emergency medicine Female Neurology (clinical) Cardiology and Cardiovascular Medicine business |
| Zdroj: | Stroke. 46:3226-3231 |
| ISSN: | 1524-4628 0039-2499 |
| DOI: | 10.1161/strokeaha.115.010985 |
| Popis: | Background and Purpose— The epidemiology of dialysis requiring acute kidney injury (AKI-D) in acute ischemic stroke (AIS) and intracerebral hemorrhage (ICH) admissions is poorly understood with previous studies being from a single center or year. Methods— We used the Nationwide Inpatient Sample to evaluate the yearly incidence trends of AKI-D in hospitalizations with AIS and ICH from 2002 to 2011. We also evaluated the trend of impact of AKI-D on in-hospital mortality and adverse discharge using adjusted odds ratios (aOR) after adjusting for demographics and comorbidity indices. Results— We extracted a total of 3 937 928 and 696 754 hospitalizations with AIS and ICH, respectively. AKI-D occurred in 1.5 and 3.5 per 1000 in AIS and ICH admissions, respectively. Incidence of admissions complicated by AKI-D doubled from 0.9/1000 to 1.7/1000 in AIS and from 2.1/1000 to 4.3/1000 in ICH admissions. In AIS admissions, AKI-D was associated with 30% higher odds of mortality (aOR, 1.30; 95% confidence interval, 1.12–1.48; P P P P Conclusions— Incidence of AKI-D complicating hospitalizations with cerebrovascular accident continues to grow and is associated with increased mortality and adverse discharge. This highlights the need for early diagnosis, better risk stratification, and preparedness for need for complex long-term care in this vulnerable population. |
| Databáze: | OpenAIRE |
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