Exhaled breath condensate hydrogen peroxide and pH for the assessment of lower airway inflammation in the horse
| Autor: | M. Duz, Sandy Love, Tim D H Parkin, Andrew Gordon Whittaker, Kris Hughes |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
viruses
Ph measurement chemistry.chemical_compound Animal science immune system diseases medicine Animals Exhaled breath condensate Horses Respiratory system Hydrogen peroxide Asthma Inflammation General Veterinary Significant difference Airway inflammation virus diseases Horse Hydrogen Peroxide Hydrogen-Ion Concentration medicine.disease respiratory tract diseases Airway Obstruction chemistry Breath Tests Exhalation Anesthesia Horse Diseases Bronchoalveolar Lavage Fluid |
| Zdroj: | Research in veterinary science. 87(2) |
| ISSN: | 1532-2661 |
| Popis: | Measurement of hydrogen peroxide (H(2)O(2)) concentration and pH in exhaled breath condensate (EBC) is useful for detection and monitoring of asthma in humans. In contrast, limited information on the use of these parameters for the investigation of lower airway inflammation (LAI) is available for horses. Aims of the current study were to investigate the intra- and inter-day variations of EBC H(2)O(2) concentration and pH in horses and establish any relationship(s) with LAI. Both intra- and inter-day variability of EBC H(2)O(2) concentration were large, while those of pH were small. No significant difference in the intra-day or inter-day H(2)O(2) concentrations or pH measurements were found in control or LAI horses, except for inter-day H(2)O(2) concentration in horses with LAI (p=0.019). There was no significant difference in EBC pH or H(2)O(2) concentration between control and LAI horses, however a trend for a reduced pH in horses with LAI was observed. |
| Databáze: | OpenAIRE |
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