Ultrafiltration and cardiopulmonary bypass associated acute kidney injury: A systematic review and meta‐analysis
| Autor: | Mohamed Abdalla Mohamed Elashhat, Edward Darling, Jeffrey B Riley, Bruce Searles, Karam R Motawea, Omneya A. Kandil, Hani Aiash, Jaffer Shah |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Clinical Investigations Subgroup analysis law.invention law Risk Factors Internal medicine Cardiopulmonary bypass medicine Humans Cardiac Surgical Procedures Cardiopulmonary Bypass business.industry Incidence (epidemiology) Acute kidney injury General Medicine Perioperative medicine.disease Confidence interval Cardiac surgery acute kidney injury fluid management Relative risk ultrafiltration Cardiology and Cardiovascular Medicine business cardiac surgery |
| Zdroj: | Clinical Cardiology |
| ISSN: | 1932-8737 0160-9289 |
| Popis: | Background Cardiopulmonary bypass is known to raise the risk of acute kidney injury (AKI). Previous studies have identified numerous risk factors of cardiopulmonary bypass including the possible impact of perioperative ultrafiltration. However, the association between ultrafiltration (UF) and AKI remains conflicting. Thus, we conducted a meta‐analysis to further examine the relationship between UF and AKI. Hypothesis Ultrafiltration during cardiac surgery increases the risk of developping Acute kidney Injury. Methods We searched PubMed, Web of Science, EBSCO, and SCOPUS through July 2021. The RevMan (version 5.4) software was used to calculate the pooled risk ratios (RRs) and mean differences along with their associated confidence intervals (95% CI). Results We identified 12 studies with a total of 8005 patients. There was no statistically significant difference in the incidence of AKI between the group who underwent UF and the control group who did not (RR = 0.90, 95% CI = 0.64−1). Subgroup analysis on patients with previous renal insufficiency also yielded nonsignificant difference (RR = 0.84, 95% CI = 0.53 −1.33, p = .47). Subgroup analysis based on volume of ultrafiltrate removed (> or |
| Databáze: | OpenAIRE |
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