Asystole during treatment with amiodarone in a patient with persistent atrial tachycardia
Autor: | Chien-Suu Kuo, Mark V. Paciotti, C.Pratap Reddy |
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Rok vydání: | 1985 |
Předmět: |
Adult
Digoxin medicine.medical_specialty Amiodarone Propanolamines Electrocardiography Pharmacotherapy Heart Rate Nadolol Tachycardia Internal medicine medicine Humans Heart Atria Asystole Atrial tachycardia Benzofurans medicine.diagnostic_test business.industry Arrhythmias Cardiac medicine.disease Heart Arrest Discontinuation Anesthesia Cardiology Drug Therapy Combination Female medicine.symptom Cardiology and Cardiovascular Medicine business Anti-Arrhythmia Agents medicine.drug |
Zdroj: | Journal of Electrocardiology. 18:105-109 |
ISSN: | 0022-0736 |
DOI: | 10.1016/s0022-0736(85)80041-8 |
Popis: | During treatment with amiodarone, digoxin and nadolol, asystole occurred repeatedly in a patient with chronic persistent automatic atrial tachycardia. Asystole did not occur after discontinuation of drug therapy, and rechallenge with amiodarone alone produced marked overdrive suppression of all pacemakers resulting in asystole. Amiodarone serum level was within therapeutic range. The possible electrophysiologic mechanisms by which amiodarone might suppress both normal and abnormal pacemakers are discussed. The occurrence of asystole at therapeutic serum concentration of amiodarone suggests that this drug should be used with caution. |
Databáze: | OpenAIRE |
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