Association of total homocysteine with blood pressure in a general population of Chinese adults: a cross-sectional study in Jiangsu province, China
| Autor: | Jianping Li, Huiyuan Guo, Yuanyuan Zhang, Yun Song, Yaren Yu, Tao Zhang, Qianyun Ban, Xiping Xu, Tonghua Zang, Binyan Wang, Chengzhang Liu, Yong Huo, Genfu Tang, Hao Zhang, Jingping Zhang, Yan Zhang, Xianhui Qin, Hongxu Wu, Dong Yan, Jingjing Cao, Lulu Chen |
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| Rok vydání: | 2018 |
| Předmět: |
Male
China hypertension Total homocysteine Cross-sectional study medicine.drug_class Epidemiology Population Adult population 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Risk Factors Medicine Humans education Antihypertensive drug Homocysteine Aged education.field_of_study business.industry Research total homocysteine Chinese adults blood pressure General Medicine Middle Aged alcohol drinking Blood pressure Cross-Sectional Studies Logistic Models Multivariate Analysis Linear Models Female business 030217 neurology & neurosurgery Demography |
| Zdroj: | BMJ Open |
| ISSN: | 2044-6055 |
| Popis: | Objectives We aimed to evaluate the relation of total homocysteine (tHcy) concentrations with systolic blood pressure (SBP) and diastolic blood pressure (DBP) levels, and examine the possible modifiers in the association among a general population of Chinese adults. Design A cross-sectional study. Setting The study was conducted within 21 communities in Lianyungang of Jiangsu province, China. Participants A total of 26 648 participants aged ≥35 years and with no antihypertensive drug use were included in the final analysis. Results Overall, there was a positive association between tHcy concentrations and SBP (per 5 μmol/L tHcy increase: adjusted β=0.45 mm Hg; 95% CI 0.29 to 0.61) or DBP levels (per 5 μmol/L tHcy increase: adjusted β=0.47 mm Hg; 95% CI 0.35 to 0.59). Compared with participants with tHcy |
| Databáze: | OpenAIRE |
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