Orbital Nerve Seath Myxoma with Extraocular Muscle Involvement: A Rare Case
| Autor: | Cristina González-García, Juan A Troyano-Rivas, Juan J Ortiz-Zapata, Nicolás Toledano-Fernández, Julian Garcia-Feijoo, Reinaldo Chícharo-de-Freitas, Luis Ortega-Medina, Ignacio Rodriguez-Una |
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| Rok vydání: | 2014 |
| Předmět: |
Pathology
medicine.medical_specialty genetic structures CD34 Antigens CD34 Malignancy Extraocular muscles Neurothekeoma Lesion Quadrant (abdomen) Fluorodeoxyglucose F18 Biomarkers Tumor medicine Humans Aged business.industry S100 Proteins Myxoma Lateral rectus muscle General Medicine Anatomy medicine.disease Immunohistochemistry Magnetic Resonance Imaging eye diseases Neoplasm Proteins Ophthalmology medicine.anatomical_structure Oculomotor Muscles Positron-Emission Tomography Orbital Neoplasms Female medicine.symptom Tomography X-Ray Computed business |
| Zdroj: | Seminars in Ophthalmology. 30:316-320 |
| ISSN: | 1744-5205 0882-0538 |
| DOI: | 10.3109/08820538.2013.874471 |
| Popis: | A 66-year-old woman with breast cancer presented with a painless mass in the left orbit. MRI revealed a well-defined intraconal mass in the temporal quadrant of the orbit. Fifteen months later, a further MRI indicated the mass had grown, displacing the left optic nerve and making contact with the lateral rectus muscle, suggesting its possible intramuscular origin. Despite the clinical and radiological characteristics of the lesion and its slow growth, a PET/CT study was developed because of the history of malignant disease. No metabolic activity of the mass or malignant lesion in other locations was observed. After surgical excision, histopathological examination revealed an abundant myxoid matrix with few spindle-shaped cells and no signs of malignancy. The cells were immunopositive for CD34, positive for S-100 protein, and negative for EMA, actin, and CD57. A diagnosis was made of a nerve sheath myxoma. The orbital location of these tumors is extremely rare. |
| Databáze: | OpenAIRE |
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