Update on the Mechanisms of Antibiotic Resistance and the Mobile Resistome in the Emerging Zoonotic Pathogen Streptococcus suis
| Autor: | Nathalie Leblond-Bourget, Eric Jouy, Virginie Libante, Manon Dechêne-Tempier, Corinne Marois-Créhan, Sophie Payot |
|---|---|
| Přispěvatelé: | Laboratoire de Ploufragan-Plouzané-Niort [ANSES], Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Dynamique des Génomes et Adaptation Microbienne (DynAMic), Université de Lorraine (UL)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
plasmids antibiotic resistance Streptococcus suis medicine.drug_class QH301-705.5 ICEs [SDV]Life Sciences [q-bio] Antibiotics competence Review Biology GIs Microbiology biofilm IMEs 03 medical and health sciences Antibiotic resistance Plasmid prophages Virology medicine Biology (General) Prophage 030304 developmental biology 0303 health sciences mechanisms 030306 microbiology resistance genes mobile genetic elements biology.organism_classification UCSs Resistome Horizontal gene transfer horizontal gene transfer Mobile genetic elements conjugation |
| Zdroj: | Microorganisms Microorganisms, MDPI, 2021, 9 (8), pp.1765. ⟨10.3390/microorganisms9081765⟩ Microorganisms, Vol 9, Iss 1765, p 1765 (2021) |
| ISSN: | 2076-2607 |
| Popis: | International audience; Streptococcus suis is a zoonotic pathogen causing important economic losses in swine production. The most commonly used antibiotics in swine industry are tetracyclines, beta-lactams, and macrolides. Resistance to these antibiotics has already been observed worldwide (reaching high rates for macrolides and tetracyclines) as well as resistance to aminoglycosides, fluoroquinolones, amphenicols, and glycopeptides. Most of the resistance mechanisms are encoded by antibiotic resistance genes, and a large part are carried by mobile genetic elements (MGEs) that can be transferred through horizontal gene transfer. This review provides an update of the resistance genes, their combination in multidrug isolates, and their localization on MGEs in S. suis. It also includes an overview of the contribution of biofilm to antimicrobial resistance in this bacterial species. The identification of resistance genes and study of their localization in S. suis as well as the environmental factors that can modulate their dissemination appear essential in order to decipher the role of this bacterium as a reservoir of antibiotic genes for other species. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|