Nonsuppressing normal thymus on chemical-shift MR imaging and anterior mediastinal lymphoma: differentiation with diffusion-weighted MR imaging by using the apparent diffusion coefficient
| Autor: | Sandro Massimo Priola, Dario Gned, Maria Teresa Giraudo, Andrea Veltri, Adriano Massimiliano Priola |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Lymphoma Thymus Gland Normal thymus Mediastinal Neoplasms 030218 nuclear medicine & medical imaging Diagnosis Differential Young Adult 03 medical and health sciences 0302 clinical medicine Mediastinal Lymphoma Diffusion-weighted magnetic resonance Nuclear Medicine and Imaging medicine Humans Effective diffusion coefficient Radiology Nuclear Medicine and imaging Nonsuppressing normal thymus Prospective Studies Child Diffusion-Weighted MR Imaging Apparent diffusion coefficient Chemical-shift magnetic resonance Radiology Nuclear Medicine and Imaging Neuroradiology business.industry Ultrasound Age Factors Mediastinum General Medicine medicine.disease Magnetic Resonance Imaging Mr imaging body regions Diffusion Magnetic Resonance Imaging 030220 oncology & carcinogenesis Female Radiology business |
| Popis: | To prospectively evaluate usefulness of the apparent diffusion coefficient (ADC) in differentiating anterior mediastinal lymphoma from nonsuppressing normal thymus on chemical-shift MR, and to look at the relationship between patient age and ADC. Seventy-three young subjects (25 men, 48 women; age range, 9-29 years), who underwent chemical-shift MR and diffusion-weighted MR were divided into a normal thymus group (group A, 40 subjects), and a lymphoma group (group B, 33 patients). For group A, all subjects had normal thymus with no suppression on opposed-phase chemical-shift MR. Two readers measured the signal intensity index (SII) and ADC. Differences in SII and ADC between groups were tested using t-test. ADC was correlated with age using Pearson correlation coefficient. Mean SII±standard deviation was 2.7±1.8% for group A and 2.2±2.4% for group B, with no significant difference between groups (P=.270). Mean ADC was 2.48±0.38x10-3mm2/s for group A and 1.24±0.23x10-3mm2/s for group B. A significant difference between groups was found (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|