Electrocardiogram abnormalities and heart rate variability in predicting mortality and cardiovascular events among hemodialyzed patients
| Autor: | Raluca Dumea, Antoniu Petris, Adrian Covic, Alexandru Burlacu, Luminita Voroneanu, Simona Hogas, Dimitrie Siriopol, Silvia Badarau, Angelica Gramaticu, Mihaela Blaj, Daniela Drugus |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Urology Myocardial Infarction QT interval Asymptomatic Coronary artery disease QRS complex Heart Rate Predictive Value of Tests Renal Dialysis Cause of Death Internal medicine Heart rate medicine Humans Heart rate variability Longitudinal Studies Prospective Studies cardiovascular diseases Myocardial infarction PR interval Aged Proportional Hazards Models business.industry Middle Aged medicine.disease Stroke Nephrology Electrocardiography Ambulatory Cardiology Kidney Failure Chronic Female medicine.symptom business |
| Zdroj: | International Urology and Nephrology. 47:1703-1708 |
| ISSN: | 1573-2584 0301-1623 |
| Popis: | The aim of the study was to evaluate the correlation between electrocardiographic parameters and heart rate variability with cardiovascular events and mortality among chronic hemodialysis patients. In this prospective study, we enrolled 116 asymptomatic patients in whom we performed ambulatory 24-h electrocardiographic Holter monitoring and before and after hemodialysis electrocardiographs. We measured the interval (PR, QRS, QTc, QTc dispersion) differences on the surface electrocardiographs and obtained frequency-domain measures from Holter monitoring (VLF, LF, HF and the LF/HF ratio). During the follow-up period, 13 participants died (11.2 %) and 16 (13.8 %) patients experienced a cardiovascular event. The pre–post-dialysis difference in QTc interval was the best predictor for cardiovascular events (95 % CI 0.453–0.786), while pre-dialysis QRS interval was the predictor for all-cause mortality (95 % CI 1.134–3.136). Also, both outcomes were predicted by pre–post-dialysis difference in PR interval and VLF. Interval changes during hemodialysis are predictive for cardiovascular events and mortality. Autonomic dysfunction and changes in PR should be monitored routinely, particularly in patients with suspected coronary artery disease. |
| Databáze: | OpenAIRE |
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