Electron Microscopic Studies on the Identification of Secretory Granules in the Parathyroid Gland of Several Animals by Means of Acid Phosphatase Reaction

Autor: Takao Setoguti, Yoshiki Goto
Rok vydání: 1974
Předmět:
Zdroj: Archivum histologicum japonicum. 36:379-389
ISSN: 0004-0681
Popis: The acid phosphatase activity in the parathyroid of mice, rats, dogs and newts was observed by electron microscopy to distinguish mature secretory granules from lysosomal dense bodies.In the parenchymal cell reactive and non-reactive granules were both present. Most of the non-reactive granules were membrane-bounded, electron moderately dense to highly dense, round, homogeneous bodies with a finely particulate texture. Such granules were similar in fine structure to so-called prosecretory granules in the Golgi area and were concluded to be mature secretory granules. Some other non-reactive granules, including both vacuoles with a finely granular content and so-called multivesicular bodies, were thought to originate from secretory granules.The maximum size of these mature secretory granules was different in various animal species and reached 0.7μ in mice, rats, and newts, whereas 0.5μ in dogs.In newts, gradual transformation of secretory granules, especially tubule-containing granules, into lysosomes was indicated.
Databáze: OpenAIRE