Blood use and transfusion needs at a large health care system in Washington state during the SARS‐CoV ‐2 pandemic

Autor: Elizabeth M. Staley, Terry Gernsheimer, Erin E Tuott, Guido Cataife, Nina Senn, John R. Hess, Hamilton C. Tsang, Christine B. Clark, Monica B. Pagano, Kleber Yotsumoto Fertrin
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Adult
Male
Risk
Washington
medicine.medical_specialty
Anemia
medicine.medical_treatment
Immunology
Blood Loss
Surgical
Blood Donors
Comorbidity
030204 cardiovascular system & hematology
Logistic regression
Severity of Illness Index
law.invention
03 medical and health sciences
Young Adult
0302 clinical medicine
Extracorporeal Membrane Oxygenation
law
Internal medicine
Pandemic
medicine
Extracorporeal membrane oxygenation
Humans
Immunology and Allergy
Platelet
Blood Transfusion
Pandemics
Aged
Blood type
Aged
80 and over
Health Services Needs and Demand
business.industry
SARS-CoV-2
Medical record
COVID-19
Hematology
Middle Aged
medicine.disease
Intensive care unit
Hospitalization
Blood Group Antigens
Female
business
Delivery of Health Care
Procedures and Techniques Utilization
030215 immunology
Zdroj: Transfusion
ISSN: 1537-2995
0041-1132
DOI: 10.1111/trf.16051
Popis: BACKGROUND: This report evaluates hospital blood use trends during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, and identifies factors associated with the need for transfusion and risk of death in patients with coronavirus 2019 (COVID-19). METHODS: Overall hospital blood use and medical records of adult patients with COVID-19 were extracted for two institutions. Multivariate logistic regression models were conducted to estimate associations between the outcomes transfusion and mortality and patient factors. RESULTS: Daily blood use decreased compared to pre-COVID-19 levels; the effect was more significant for platelets (29% and 34%) compared to red blood cells (25% and 20%) at the two institutions, respectively. Surgical and oncologic services had a decrease in average daily use of platelets of 52% and 30%, and red blood cells of 39% and 25%, respectively. A total of 128 patients with COVID-19 were hospitalized, and 13 (10%) received at least one transfusion due to anemia secondary to chronic illness (n = 7), recent surgery (n = 3), and extracorporeal membrane oxygenation (n = 3). Lower baseline platelet count and admission to the intensive care unit were associated with increased risk of transfusion. The blood group distribution in patients with COVID-19 was 37% group O, 40% group A, 18% group B, and 5% group AB. Non-type O was not associated with increased risk of mortality. CONCLUSION: The response to the SARS-CoV-2 pandemic included changes in routine hospital operations that allowed for the provision of a sufficient level of care for patients with and without COVID-19. Although blood type may play a role in COVID-19 susceptibility, it did not seem to be associated with patient mortality.
Databáze: OpenAIRE
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