Characteristics of tobacco-related lung diseases in Fukuoka Prefecture, Japan: A prospective, multi-institutional, observational study
| Autor: | Shohei Takata, Yoichi Nakanishi, Toru Tsuda, Masaki Fujita, Yasuhiko Kitasato, Saiko Ogata-Suetsugu, Kazuhiro Yatera, Tomoaki Hoshino, Chiharu Yoshii, Kentaro Watanabe, Nobuhiko Nagata, Naoki Hamada, Naoyuki Inoue, Hiroshi Mukae, Shoji Tokunaga |
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| Rok vydání: | 2019 |
| Předmět: |
Pulmonary and Respiratory Medicine
Lung Diseases medicine.medical_specialty Exacerbation Disease Pulmonary function testing 03 medical and health sciences 0302 clinical medicine Japan Internal medicine Medicine Humans 030212 general & internal medicine Prospective Studies Idiopathic interstitial pneumonia COPD Lung business.industry Smoking medicine.disease Combined pulmonary fibrosis and emphysema respiratory tract diseases medicine.anatomical_structure 030228 respiratory system Observational study business |
| Zdroj: | Respiratory investigation. 58(1) |
| ISSN: | 2212-5353 |
| Popis: | Background Tobacco smoking causes a variety of smoking-related diseases, death, and economic damage. Despite targeted anti-smoking campaigns, tobacco-related deaths are expected to increase in Japan. We investigated the current state of non-cancerous lung diseases such as idiopathic interstitial pneumonias (IIPs), chronic obstructive pulmonary disease (COPD), and combined pulmonary fibrosis and emphysema (CPFE), which are known to be highly related to tobacco smoking. Methods This prospective multi-institutional observational study involved 29 major hospitals within the Fukuoka Prefecture area (Fukuoka tobacco-related lung disease registry study group). Patients diagnosed with IIPs, including CPFE and COPD, registered from September 1, 2013 to April 30, 2016 were included. Clinical background information, laboratory and pulmonary function test results, findings of imaging tests, including chest radiography and chest computed tomography, and DNA isolated from peripheral blood were collected from each patient. Follow-up surveillance involved collection of data regarding the exacerbation of disease and death until 5 years of registration. In the present study, we report the baseline characteristics of the patients registered in this surveillance study. Results Overall, 1016 patients (524 with IIPs, including 145 CPFE and 492 with COPD) were enrolled. Among the patients with COPD, 96.8% were current or former smokers. Among the patients with IIPs, 69.9% were current or former smokers. Conclusion This study revealed the current status of lung diseases potentially related to tobacco smoking in Fukuoka Prefecture. Both COPD and CPFE were highly related to tobacco smoking, whereas 30% of patients with IIPs had never smoked. |
| Databáze: | OpenAIRE |
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