Long-term effects of 2 energy-restricted diets differing in glycemic load on dietary adherence, body composition, and metabolism in CALERIE: a 1-y randomized controlled trial

Autor: Manjushri Bhapkar, Susan B. Roberts, Paul J. Fuss, Rachel A. Cheatham, Julie K. Golden, Chhanda Dutta, Cheryl H. Gilhooly, Michelle Tsay, Alice H. Lichtenstein, Stephanie Tyler, Edward Saltzman, Gerard E. Dallal, Anastassios G. Pittas, Sai Krupa Das, James P. DeLany, Megan A. McCrory
Rok vydání: 2007
Předmět:
Zdroj: The American Journal of Clinical Nutrition. 85:1023-1030
ISSN: 0002-9165
DOI: 10.1093/ajcn/85.4.1023
Popis: Background:Thereremainsnoconsensusabouttheoptimaldietary composition for sustained weight loss. Objective: The objective was to examine the effects of 2 dietary macronutrient patterns with different glycemic loads on adherence to a prescribed regimen of calorie restriction (CR), weight and fat loss, and related variables. Design: A randomized controlled trial (RCT) of diets with a high glycemic load (HG) or a low glycemic load (LG) at 30% CR was conducted in 34 healthy overweight adults with a mean (! SD) age of35! 6yandbodymassindex(kg/m 2 )of27.6! 1.4.Allfoodwas providedfor6moindietscontrolledforconfoundingvariables,and subjectsself-administeredtheplansfor6additionalmonths.Primary andsecondaryoutcomesincludedenergyintakemeasuredbydoubly labeled water, body weight and fatness, hunger, satiety, and resting metabolic rate. Results: All groups consumed significantly less energy during CR than at baseline (P " 0.01), but changes in energy intake, body weight, body fat, and resting metabolic rate did not differ significantly between groups. Both groups ate more energy than provided (eg,21%and28%CRat3moand16%and17%CRat6mowithHG and LG, respectively). Percentage weight change at 12 mo was # 8.04! 4.1%intheHGgroupand# 7.81! 5.0%intheLGgroup. There was no effect of dietary composition on changes in hunger, satiety, or satisfaction with the amount and type of provided food during CR. Conclusions: These findings provide more detailed evidence to suggest that diets differing substantially in glycemic load induce comparable long-term weight loss. Am J Clin Nutr 2007;85: 1023‐30.
Databáze: OpenAIRE