Neurotensin in hypothalamo-hypophyseal portal blood
| Autor: | S.L. Lightman, D.J.A. Eckland |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Male
medicine.medical_specialty Hypothalamus Stimulation complex mixtures chemistry.chemical_compound Internal medicine medicine Animals Secretion Molecular Biology Neurotensin business.industry musculoskeletal neural and ocular physiology General Neuroscience digestive oral and skin physiology Peripheral plasma Rats Inbred Strains Electric Stimulation Rats Endocrinology nervous system chemistry Pituitary Gland Median eminence Portal blood Neurology (clinical) business hormones hormone substitutes and hormone antagonists Developmental Biology |
| Zdroj: | Brain Research. 421:161-166 |
| ISSN: | 0006-8993 |
| Popis: | The control of hypothalamo-hypophyseal neurotensin secretion was studied using a modification of the Worthington-Fink portal samplimg technique. Portal concentrations of neurotensin were significantly greater than the concentrations found in peripheral plasma, and HPLC characterisation demonstrated that both portal and peripheral plasma neurotensin were very similar. Two different anaesthetic agents, urethane and althesin, did not differ in the resulting portal concentrations of neurotensin. Electrical stimulation of the median eminence resulted in a very marked increase in portal neurotensin concentration. |
| Databáze: | OpenAIRE |
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