Development of Triphenylamine Functional Dye for Selective Photoelectrochemical Sensing of Cysteine
| Autor: | Cheng He, Jun Ni, Honglei Song, Xiuyun Wang, Shuo Wu, Jie Song, Yanqiu Zhao |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
chemistry.chemical_classification
Photocurrent Aniline Compounds biology Chemistry Active site Electron donor Electrochemical Techniques Electron acceptor Photochemical Processes Photochemistry Triphenylamine Analytical Chemistry chemistry.chemical_compound Spectrometry Fluorescence Spectroscopy Fourier Transform Infrared biology.protein Thiophene Michael reaction Moiety Spectrophotometry Ultraviolet Cysteine Coloring Agents |
| Zdroj: | Analytical Chemistry. 86:5922-5928 |
| ISSN: | 1520-6882 0003-2700 |
| DOI: | 10.1021/ac500790u |
| Popis: | A novel triphenylamine-based organic dye, TTA, with an acrylic group is designed to graft TiO2 nanoparticles for sensitive and selective photoelectrochemical sensing. The synthesized TTA possesses a high molar absorption coefficient, leading to an enhanced photoelectron emission ability of the electron donor. The carboxyl group of TTA acts as not only an electron acceptor but also a linker to connect TTA to TiO2 nanoparticles. Under irradiation, TTA shows fast intramolecular charge transfer from triphenylamine to carboxyl group via the π-bridge of thiophene moiety, thus producing a sensitive photocurrent response. Meanwhile, the acrylic moiety provides an active site for the Michael addition reaction, which would destroy the π-bridge and decrease the photocurrent response. Thus, a selective photoelectrochemical sensing strategy is proposed for detection of small biomolecules. Using cysteine as a model analyte, this sensing strategy shows a detectable range from 1 to 200 μM, without the interference from natural amino acids and various biological reducing reagents. This work offers a new photoelectrochemical route to highly selective and sensitive detection of biologically important small molecules. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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