BRI1 and BAK1 interact with G proteins and regulate sugar-responsive growth and development in Arabidopsis
| Autor: | Lei-Ying Zheng, Yingchun Wang, Wuxia Liu, Yunhai Li, Beijiu Cheng, Liangliang Chen, Yueying Zhang, Zupei Liu, Ran Xu, Shengjun Li, Jingjing Kong, Xiahe Huang, Yuancheng Peng |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0106 biological sciences
0301 basic medicine G protein Science Arabidopsis General Physics and Astronomy Plasma protein binding Protein Serine-Threonine Kinases 01 natural sciences Article General Biochemistry Genetics and Molecular Biology 03 medical and health sciences Plant Growth Regulators GTP-Binding Proteins Gene Expression Regulation Plant Phosphorylation lcsh:Science Sugar Regulation of gene expression Microscopy Confocal Multidisciplinary biology Arabidopsis Proteins Chemistry Cell Membrane Genetic Complementation Test fungi food and beverages General Chemistry Plants biology.organism_classification Culture Media Cell biology Glucose 030104 developmental biology Microscopy Fluorescence Mutation Seeds lcsh:Q Signal transduction Sugars Protein Kinases Function (biology) Protein Binding Signal Transduction 010606 plant biology & botany |
| Zdroj: | Nature Communications Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018) |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/s41467-018-03884-8 |
| Popis: | Sugars function as signal molecules to regulate growth, development, and gene expression in plants, yeasts, and animals. A coordination of sugar availability with phytohormone signals is crucial for plant growth and development. The molecular link between sugar availability and hormone-dependent plant growth are largely unknown. Here we report that BRI1 and BAK1 are involved in sugar-responsive growth and development. Glucose influences the physical interactions and phosphorylations of BRI1 and BAK1 in a concentration-dependent manner. BRI1 and BAK1 physically interact with G proteins that are essential for mediating sugar signaling. Biochemical data show that BRI1 can phosphorylate G protein β subunit and γ subunits, and BAK1 can phosphorylate G protein γ subunits. Genetic analyses suggest that BRI1 and BAK1 function in a common pathway with G-protein subunits to regulate sugar responses. Thus, our findings reveal an important genetic and molecular mechanism by which BR receptors associate with G proteins to regulate sugar-responsive growth and development. G-proteins regulate sugar-responsive growth in plants. Here the authors show that brassinosteroid (BR) signaling is also involved in sugar responses and present evidence that the BR receptor BRI1 and its co-receptor BAK1 can phosphorylate G-protein subunits to regulate sugar signaling in Arabidopsis. |
| Databáze: | OpenAIRE |
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